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Open studies

Study

ASPIRIN trial

A Phase III double-blind placebo-controlled Randomised Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients

Study

CAIRO 6 (gesloten voor inclusie)

Perioperative systemic therapy and cytoreductive surgery with HIPEC  versus upfront cytoreductive surgery with HIPEC alone for resectable colorectal peritoneal metastases: a multicentre, open-label, parallel-group, phase II-III, randomised superiority study.

Study

CAIRO 7

Radioembolization with 166Ho-microspheres in elderly and/or fragile patients with previously untreated unresectable liver-only metastases of colorectal cancer, CAIRO7 study endorsed by the Dutch Colorectal Cancer Group (DCCG)

Study

CAMINO

Clinical added value of MRI over CT in patients scheduled for colorectal liver metastases resection  

Study

COLLISION

COLLISION trial: Colorectal liver metastases: surgery versus thermal ablation – a phase III single-blind prospective randomized controlled trial

Study

COLLISION RELAPSE

COLLISION RELAPSE Trial - Recurrent Colorectal Liver Metastases: Repeat Local Treatment +/- Neoadjuvant Systemic Therapy - a Phase III Prospective Randomized Controlled Trial

Study

COLLISION-XL trial

Unresectable colorectal liver metastases: stereotactic body radiotherapy versus microwave ablation – a phase II prospective randomized controlled trial for CRLM 3-5 cm

Study

COLOPEC II

Second and third look laparoscopy in pT4 colon cancer patients for early detection of peritoneal metastases; a randomized multicentre trial.

Study

COLOR III

A MULTICENTRE RANDOMISED CLINICAL TRIAL COMPARING TRANSANAL TME VERSUS LAPAROSCOPIC TME FOR MID AND LOW RECTAL CANCER

Study

DOSAGE

A multicenter randomized phase III trial of upfront DOSe-reduced Chemotherapy for Advanced Colorectal Cancer in Elderly patients   

Study

FIT

Multicentre randomized controlled trial comparing ferric(III)carboxymaltose infusion with oral iron supplementation in the treatment of preoperative anaemia in colorectal cancer patients

Study

IMARI

Multi-Interventional program for prevention and early Management of Anastomotic leakage after total mesorectal excision in Rectal cancer patIents, the IMARI-trial

Study

INTERACT

Concomitant intraperitoneal and systemic chemotherapy in patients with extensive peritoneal carcinomatosis of colorectal origin

Study

INTERACT-II

Intraperitoneal irinotecan with concomitant FOLFOX and bevacizumab for patients with unresectable colorectal peritoneal metastases – a phase II study.

Study

LaNoReC

Lateral Nodal Recurrence in Rectal Cancer

Study

MEND-IT

Neo-adjuvant FOLFOXIRI and chemoradiotherapy for high risk (“ugly”) locally advanced rectal cancer

Study

MOCCAS

  Molecular stool testing for Colorectal CAncer Surveillance (MOCCAS) study

Study

OPAXX

OPAXX: Organ Preservation in patients with a good clinical response after neoadjuvant (chemo)radiation for rectal cancer: optimization of treatment strategies and defining the role of Adittional contact X-ray Brachytherapy versus eXtending the waiting interval and local excision

Study

ORCHESTRA

A randomized multicenter clinical trial for patients with multi-ORgan, Colorectal cancer metastases comparing the combination of cHEmotherapy and maximal tumor debulking versuS chemoTheRapy Alone

Study

PelvEx II

Multicenter, open-label, randomised, controlled, parallel arms clinical trial of induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer

Study

PIPAC-II

Bidirectional treatment consisting of repetitive laparoscopic electrostatic pressurized intraperitoneal aerosol chemotherapy with oxaliplatin (ePIPAC-OX) and systemic intravenous chemotherapy for isolated unresectable colorectal peritoneal metastases: feasibility, safety, tolerability, and preliminary efficacy

Study

PLCRC

Prospective Dutch CRC Cohort (PLCRC)

Study

Prospectieve data verzameling van het gebruik van S-1 (TeysunoR) in de adjuvante behandeling van het colorectaal carcinoom in Nederland.

Prospectieve data verzameling van het gebruik van S-1 (TeysunoR) in de adjuvante behandeling van het colorectaal carcinoom in Nederland.

Study

PUMP-III trial

Adjuvant hepatic arterial infusion pump chemotherapy after repeat hepatectomy for patients with liver confined recurrence of colorectal cancer – a phase II study

Study

PUMP-IT pilot

Hepatic arterial infusion PUMP chemotherapy combined with systemic chemoTherapy for potentially resectable colorectal liver metastases. The PUMP-IT study”

Study

PUMP trial

Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk score – a randomized controlled trial  

Study

RIGHT

Implementation of optimized and standardized surgical technique for right-sided colon cancer: a prospective interventional sequential cohort study with a transition period

Study

STAR-TREC phase 3

Can we Save the rectum by Watchful waiting or TransAnal microsurgery following (chemo)Radiotherapy versus Total mesorectal excision for early Rectal Cancer?

Study

TESAR

A Multi-centre randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer

Study

The CONSTRUCT registry

Evidence-based treatment of patients with acute left-sided malignant colonic obstruction: Applying a clinical decision guideline.

Study

TRIASSIC

Multicentre, randomised controlled trial comparing TRansanal minimal InvAsive Surgery (TAMIS) and endoscopic Submucosal dIsseCtion (ESD) for resection of non-pedunculated rectal lesions