Name of the study
Prospective Dutch CRC Cohort (PLCRC)
Researchers and contact information
Contact information project manager
Dr. G.R. Vink
3511 DT Utrecht
Contact information coordinating investigator
Dr. M. Koopman,
UMC Utrecht, Afdeling Medische Oncologie
3508 GA Utrecht
088 - 755 8528
PLCRC is a population-based observational cohort study for all patients diagnosed with colorectal cancer (CRC) in the Netherlands. The aim is to establish a continuous source for a large variety of research purposes. For this project, data will prospectively be collected on tumor characteristics, pathology results, medical history, comorbidities, medication use, basic physical examination, imaging results, treatment, treatment outcomes, hospital stays, interventions and grade 3/4 (serious) adverse events.
Participating patients will be invited to complete validated questionnaires on self-reported Health Related Quality of Life (HRQoL) and work ability, and to donate blood and tumor tissue samples for future research purposes. This cohort of colorectal cancer patients will further be used for other (future) studies, for example studies to evaluate the impact of diet and lifestyle on treatment response, or to evaluate new treatment modalities according to the cohort multiple randomized controlled trial design.
PLCRC is supported by the Dutch Colorectal Cancer Group (DCCG) and collaborates with various organizations like the Netherlands comprehensive cancer organisation (IKNL), BBMRI, Profiles, and many others.
Participating centers and contact information center/doctors
- St Antonius Ziekenhuis
- Deventer Ziekenhuis
- Diakonessenhuis Utrecht
- Erasmus MC
- Ikazia Ziekenhuis
- Meander Medisch Centrum
- Ziekenhuis Rivierenland
- Spaarne Gasthuis
- Zuwe Hofpoort Ziekenhuis