Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC Dutch randomized multicentre trial.
Pelvic Floor Rehabilitation to improve functional Outcome and quality of life after surgery for Rectal CancEr: a randomized controlled trial.
A phase III study of first-line Pembrolizumab (MK-3475) versus chemotherapy in microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal carcinoma
Randomized Multicentre Phase III study of short course radiation therapy followed by prolonged pre-operative chemotherapy and surgery in primary high risk rectal cancer compared to standard chemoradiotherapy and surgery and optional adjuvant chemotherapy.
An open-label, randomised, phase 2 study comparing S 95005 plus bevacizumab to capecitabine plus bevacizumab in patients with previously untreated metastatic colorctal cancer who are non-eligible for intensive therapy