Acronym
RAPIDO
Name of the study
Randomized Multicentre Phase III study of short course radiation therapy followed by prolonged pre-operative chemotherapy and surgery in primary high risk rectal cancer compared to standard chemoradiotherapy and surgery and optional adjuvant chemotherapy.
Researchers and contact information
LUMC Clinical Research Center
A.G.H. Roodvoets or E. Meershoek - Klein Kranenbarg
Leiden University Medical Center
Clinical Research Center, K6-R
P.O. Box 9600, 2300 RC LEIDEN, the Netherlands
Phone: +31-71-526 3500, Fax: +31-71-526 6744
E-mail: clinicalresearchcenter@lumc.nl
URL: https://dccg.nl/trial/rapido
Summary study
Short course radiation therapy followed by prolonged pre-operative chemotherapy and surgery in primary high risk rectal cancer compared to standard chemoradiotherapy and surgery and optional adjuvant chemotherapy.
Intervention
Arm A: Long course chemoradiotherapy followed by surgery. Arm B: Short course 5 x 5 Gy radiotherapy, followed by combination chemotherapy and surgery
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Netherlands, The |
EINDHOVEN [Catharina Zkh] |
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Netherlands, The |
LEIDEN [LUMC] |
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Netherlands, The |
ALKMAAR [Noord West ZHG] |
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Netherlands, The |
AMSTERDAM [AMC] |
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Netherlands, The |
AMSTERDAM [NKI/AvL] |
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Netherlands, The |
AMSTERDAM [OLVG] |
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Netherlands, The |
AMSTERDAM [VUMC] |
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Netherlands, The |
ASSEN [Wilhelmina Zkh] |
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Netherlands, The |
BREDA [Amphia Zkh] |
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Netherlands, The |
DELFT [RDGG] |
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Netherlands, The |
DEN HAAG [HaGa Zkh] |
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Netherlands, The |
DEN HAAG [MCH-Bronovo] |
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Netherlands, The |
DEVENTER [Deventer Zkh] |
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Netherlands, The |
GOUDA [Groene Hart Zkh] |
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Netherlands, The |
GRONINGEN [Martini Zkh] |
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Netherlands, The |
GRONINGEN [UMCG] |
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Netherlands, The |
HEERENVEEN [Zkh Tjongerschans] |
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Netherlands, The |
HENGELO [ZGT] |
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Netherlands, The |
HOOFDDORP [Spaarne Gasthuis] |
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Netherlands, The |
LEEUWARDEN [MCL] |
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Netherlands, The |
LEIDERDORP [Alrijne Zkh] |
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Netherlands, The |
NIJMEGEN [Radboudumc] |
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Netherlands, The |
SNEEK [Antonius Zkh] |
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Netherlands, The |
UTRECHT [Diakonessenhuis] |
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Netherlands, The |
ZWOLLE [Isala Klinieken] |
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Denmark |
AALBORG [Aalborg Universitetshosp] |
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Denmark |
ODENSE [Universitetshospital] |
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Norway |
KRISTIANSAND [Sørlandet Sykehus] |
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Norway |
OSLO [Universitetssykehus] |
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Slovenia |
LJUBLJANA [Onkološki Inštitut] |
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Spain |
BARCELONA [Hosp. Vall d'Hebron] |
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Spain |
LLOBREGAT [ICO Hospitalet] |
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Spain |
MADRID [Hospital Ramón y Cajal] |
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Spain |
VALENCIA [Cons.Hosp. Gen.Univ.] |
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Spain |
VALENCIA [Hosp. Clín. Universit] |
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Spain |
VALENCIA [Hospital La Fe] |
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Sweden |
BORÅS [Södra Älvsborgs Sjukhus] |
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Sweden |
ESKILSTUNA [Mälarsjukhuset] |
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Sweden |
FALUN [Falu Lasarett] |
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Sweden |
GÄVLE [Gävle Sjukhus] |
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Sweden |
GÖTEBORG [Sahlgrenska Uni.sjukh] |
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Sweden |
KALMAR [Lanssjukhuset] |
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Sweden |
KARLSTAD [Centralsjukhuset] |
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Sweden |
LINKÖPING [Universitet] |
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Sweden |
LUND [Universitetssjukhuset] |
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Sweden |
ÖREBRO [Universitetssjukhuset] |
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Sweden |
SKÖVDE [Skaraborgs Sjukhus] |
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Sweden |
STOCKHOLM [Karolinska] |
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Sweden |
SUNDSVALL [Sundsvalls Sjukhus] |
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Sweden |
UMEÅ [Norrlands Univ. sjukhus] |
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Sweden |
UPPSALA [Akademiska Sjukhuset] |
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Sweden |
VÄSTERÅS [Centrallasarett] |
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Sweden |
VÄXJÖ [Centrallasarettet] |
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United States |
ST LOUIS [Siteman Cancer Center] |